Spontaneous dichorionic diamniotic twin pregnancy following a leuprolide acetate trigger and freeze all cycle for OHSS risk: A case report

Introduction: Gonadotropin-releasing hormone (GnRH) agonist triggers are increasingly used in antagonist vitro fertilization (IVF) cycles to prevent ovarian hyperstimulation syndrome (OHSS) following a robust response. The luteolytic effects of GnRH agonists inhibit implantation or spontaneous pregnancy, warranting freezing available blastocysts for future transfer after the risk OHSS subsides. Case Report: A 33-year-old G1P1 with secondary infertility due polycystic underwent IVF cycle. leuprolide acetate trigger final oocyte maturation was prescribed given her OHSS. dichorionic/diamniotic twin pregnancy ensued. Conclusion: This case reinforces importance advising abstinence during stimulation phase an cycle and that, although rare, endometrium may allow conception trigger, which further potentiate late